Comparative dosimetric evaluation of three-dimensional conformal and stereotactic radiotherapy for treatment of intracranial tumors.

نویسندگان

  • Manoj Gupta
  • M Babaiah
  • M Dinesh Kumar
  • Pushpendra H Hirapara
  • Arvind K Patidar
  • Rahul V Walke
چکیده

AIMS To evaluate the dosimetric profile among three-dimensional conformal radiotherapy (3D-CRT) and stereotactic radiotherapy (SRT) for the treatment of intracranial tumors. MATERIALS AND METHODS Seventeen patients with intra cranial tumors of benign nature or low malignant potential were enrolled and planned for SRT as well as 3D-CRT. Dosimetric comparison between these two plans was done considering the following parameters: Target coverage, conformity index, and heterogeneity index. RESULTS The dosimetric parameters of the 3D-CRT plans were a little inferior compared with those for the SRT plans. The difference between mean target coverage, mean conformity index and mean heterogeneity index for 3D-CRT and SRT plans was highly significant at P < 0.001 (t = 7.74), P < 0.001 (t = 5.52), and P < 0.01 (t = 3.15) respectively. CONCLUSION SRT is a very efficient treatment option for intracranial tumors, in view of better target coverage and conformality compared with 3D-CRT.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Dosimetric comparison of 3-dimensional conformal and intensity-modulated radiotherapy techniques for whole breast irradiation in the prone and supine positions

Background: The aim of this study was to compare the differences of the dosimetric parameters between three-dimensional conformal radiotherapy (3D-CRT) and simultaneous-integrated boost intensity-modulated radiotherapy (SIB-IMRT) techniques in the prone and supine positions for breast irradiation. Materials and Methods: Ten patients underwent a computed tomography simulation in both the prone a...

متن کامل

Effect of replacing cochlea contour with inner ear contour on cochlea dose-volume calculations in conventional 2 dimensional and conformal 3 dimensional radiotherapy of brain

Introduction: Sensorineural hearing loss (SNHL) is one of the possible complications of radiotherapy treatment of brain tumors. The auditory system of patients with brain tumors often is placed inside of radiation field and receives a significant amount of radiation dose resulting in hearing loss. The purpose of this study was to compare contouring and delivery dose to cochlea...

متن کامل

Dosimetric Study of Tissue Heterogeneity Correction for Breast Conformal Radiotherapy

Introduction: Heterogeneity correction is an important parameter in dose calculation for cancer patients where it may be cause inaccuracy in dose calculation as a result of different densities of patients. This study studied the impact of dose calculation of breast cancer patients with and without heterogeneity correction. Material and Methods: Twenty breast cancer patients were treated with Th...

متن کامل

Effect of Bolus Frequency and Its Thickness in Postmastectomy Three-dimensional Conformal Radiotherapy on Skin Dose for Superposition Algorithm

Introduction: The postmastectomy radiotherapy uses bolus to improve the coverage close to the skin; however, it needs to be removed in case of severe skin toxicity. This study investigated the effect of bolus parameters (i.e., frequency and thickness) for the superposition algorithm on skin dose in postmastectomy three-dimensional conformal radiotherapy (3D-CRT). <str...

متن کامل

Stereotactic Radiosurgery/Radiotherapy: A Historical Review

"Stereotactic" is an exact radiotherapy treatment modality which implements invasive and non-invasive facilities for improving precise dose delivery. Stereotactic refers to three-dimensional localization of a specific point in space by a unique set of coordinates that relate to a fixed external reference frame. An accurate delivery of radiation is attainable using these techniques with high pre...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of the Egyptian National Cancer Institute

دوره 24 4  شماره 

صفحات  -

تاریخ انتشار 2012